A new study unveiled at the American Society of Clinical Oncology (ASCO) 2025 conference has revealed a chilling trend: alcohol-related cancer deaths in the United States have nearly doubled over the past 30 years. The research highlights a growing public health crisis, especially among men and adults aged 55 and older, and calls for urgent action on awareness, prevention, and policy.
Key Findings: Alcohol-Associated Cancer Deaths Surge
The study, which analyzed national mortality data from 1990 to 2021, found that deaths from cancers caused by alcohol jumped from 11,896 in 1990 to 23,207 in 2021—a 95% increase over three decades.
Dr. Chinmay Jani, the lead author and clinical fellow at the Sylvester Comprehensive Cancer Center, told ABC News:
“We already know about tobacco and cancer, but alcohol is a significant carcinogen as well. Even small amounts can increase your risk.”
This data challenges the long-held assumption that moderate drinking is safe, revealing that even occasional alcohol consumption can increase cancer risk.
No Safe Amount: Alcohol Is a Group-1 Carcinogen
Alcohol is classified as a Group-1 carcinogen by the International Agency for Research on Cancer (IARC)—the same category as tobacco and asbestos. It has been directly linked to seven types of cancer, including:
- Liver cancer
- Breast cancer
- Colorectal cancer
- Esophageal cancer
- Throat, larynx, and mouth cancers
The study emphasized that biological mechanisms, such as DNA damage and impaired nutrient absorption, are likely behind alcohol’s carcinogenic effects.
Men Hit Hardest: Gender Disparities in Alcohol-Related Cancer Deaths
The research revealed significant gender differences:
- Men saw a 70.2% increase in alcohol-associated cancer deaths.
- Women experienced a 15.2% increase.
This gap may be due to men’s earlier drinking onset, heavier consumption patterns, and biological differences in how alcohol is metabolized.
Geographic Variations: Washington D.C. vs. Utah
Geographic differences also emerged:
- Washington, D.C. had the highest rate of alcohol-related cancer deaths.
- Utah reported the lowest, likely due to lower statewide alcohol consumption rates.
These disparities suggest that local culture, laws, and consumption norms significantly affect cancer risk and outcomes.
Liver Cancer: A Silent and Deadly Threat
Among all cancers linked to alcohol, liver cancer was the most fatal—especially in individuals over 55. Even moderate alcohol intake elevated the risk, particularly among those with:
- Obesity
- Diabetes
- High cholesterol
The combination of alcohol use and metabolic health issues poses a compounded threat to an aging population.
Early Drinking, Long-Term Damage
Dr. Jani noted that early drinking habits have cumulative, long-lasting effects:
“When people start drinking at a younger age, the damage accumulates over time and leads to serious disease later in life.”
This underscores the importance of early education and interventions targeting youth and college-age adults.
Policy Recommendations: Time for Action
In response to the findings, public health experts are calling for:
- Warning labels on alcohol products (as supported by the U.S. Surgeon General).
- Stricter regulations on alcohol marketing.
- Public awareness campaigns on alcohol’s cancer risks.
- Enhanced school and community education programs.
- Routine screenings for at-risk individuals.
Dr. Gilberto Lopes, co-author and oncology chief at Sylvester Center, stated:
“Our study aims to drive change. The public must understand that alcohol isn’t harmless—it’s a serious cancer risk.”
Implications for Public Health and Society
This research arrives at a time when economic pressures and rising stress levels are fueling risky behaviors, including alcohol use. Without bold action, experts warn that alcohol-related cancer deaths will continue to climb, placing additional burdens on families, healthcare systems, and communities.
There is also growing concern that the glamorization of drinking in media and culture continues to downplay the real risks.
Takeaway: What You Can Do to Reduce Your Risk
Health professionals urge the public to reconsider alcohol consumption as part of cancer prevention. Here’s what you can do:
✅ Limit intake – No more than 1 drink/day for women, 2 drinks/day for men.
✅ Avoid binge drinking and high-risk alcohol use.
✅ Maintain a healthy weight and address metabolic health.
✅ Get screened regularly, especially if you have a history of alcohol use or chronic illness.
✅ Educate your children and peers about the long-term risks.
Conclusion: A National Wake-Up Call
The doubling of alcohol-related cancer deaths is not just a statistic—it’s a wake-up call for individuals, families, healthcare providers, and policymakers alike. While alcohol may be socially accepted, its carcinogenic properties are undeniable. This study brings crucial visibility to a hidden epidemic—and makes clear that real change is needed now.
Let this moment be a catalyst for a healthier future, grounded in awareness, prevention, and responsibility.